Telehealth vs. In-Person HRT for Gender-Affirming Care

Let’s talk about the way that gender-affirming hormone care is given. It starts with you finding a provider with whom you feel comfortable and meeting with that person regularly. Goal discussions, prescriptions, and lab monitoring require appointments for on-going care.

One of the most comprehensive systemic reviews on gender affirming care to date showed gender-affirming care improves quality of life, stigma, and mental health [7].  So you see, what matters here most is getting medical care if you need it. And it can’t be understated that telehealth helped expand gender-affirming care in meaningful ways. Per WPATH SOC8, "Efforts to decentralize gender-affirming care within primary care settings and establish telehealth services [are being pioneered] to reduce barriers and improve access." [4]

In my personal opinion, both telehealth and in-person options are needed – and kind of like when something goes wrong with your car, sometimes video-ing in, just isn’t enough. While many parts of gender-affirming hormone therapy (HRT or GAHT) management aren’t very complicated and don’t require an in-person evaluation, having the option for both visit types adds to the care provided.

In-person visits can add a beat to the healthcare experience – an intentionality to taking up space; whether that is having the space to emotionally tap in to your HRT experience with an experienced healthcare provider, building on the clinical relationship so that you can be better heard/seen/understood during an appointment, or accessing another point of screening for chronic illnesses like high blood pressure. And at AHM, it also means being part of a different form of HRT care – direct care that doesn’t rely on 15 minute appointments and insurance-directed medicine.


What Is Gender-Affirming Hormone Therapy?

HRT vs. GAHT β€” same thing, different language

A quick note on acronyms: HRT and GAHT are often interchanged online and while talking. In my clinical notes, however I tend to use GAHT (gender-affirming hormone therapy) as it can be more specific to transitioning.

HRT (hormone replacement therapy) is used clinically for both transgender people (GAHT: when hormones are used to induce secondary sex characteristics) as well as for cisgender people.

Sometimes when HRT is meant to be more specific to cisgender patients, people may use the term β€œbioidentical” hormone therapy; examples include taking hormones around the time of menopause to help with symptoms or replacing low levels of testosterone to help with low libido or energy. And one could totally argue that ALL of these uses are β€œgender” affirming – but there are different expected outcomes and different durations of therapy. Different letters, but only sometimes the same meaning.

What your provider is actually doing at each visit

I’m there primarily to help explain what medication effects are expected, to what degree effects are known or unknown, to ensure safety in the prescription and monitoring of the hormone medications, and to provide advice as a medical consult when there are questions about how these hormonal medication affect current, future, and co-morbid health.

Dr. John Fernandez, headshot, AHM gender-affirming provider

For prescription management, I’m there to help with finding the best dose for you. People vary when it comes to how our bodies metabolize and utilize meds, proteins, nutrition, so sometimes an individualized approach can make all the difference.

Additionally, I’m there to help find the best route of administration. Some people prefer the flexibility of a pill, some people want the convenience of a weekly shot. Let’s explore these questions to find out what works best for your gender-affirming hormone therapy.

When it comes to monitoring, this is where telehealth and in-person care benefits can start to differ. Let’s talk about some of the benefits of telehealth first.


The Real Benefits of Telehealth for HRT

Access β€” especially if you're not in LA

First and foremost – finding a provider who is a good fit for you can be challenging. Telehealth options have expanded accessibility; and I know for myself, when the drive needed to get to where I’m going starts to go over the 45 minute mark, then I’m starting to find other options so I don’t have to do that.

And in LA, those distances are a lot smaller than those in KY where I’m from. If I’m out in Oxnard, I probably don’t want to drive into West Hollywood for a 15 minute check in (although maybe if I get an Erewhon smoothie as a treat to myself afterward, it might be…)

Privacy and the waiting room problem

It’s real. Waiting in the seat where someone is going to call out your name. Asking yourself, β€œWill they call my legal name or preferred name?” β€œWill they use gendered language before I even enter the room?” This, while sitting beside strangers in a small public place. Most offices don’t have waiting room privacy, because those are public, multi-use spaces.  That’s normal. The situation can cause real anxiety, but is almost expected for many clinic spaces. β€œNormal.”

However, telehealth avoids that completely. At the time of your appointment, you can sit comfortably in a chair at home (or even at work on break - but PLEASE don’t drive and telehealth at the same time). With telehealth, the waiting room is where you want it to be, so you have more control over the environment with which the medical appointment is taking place.

Flexibility for people with complicated schedules or lives

I know it’s necessary for those in between times when a doctor’s appointment just doesn’t fit into your schedule. That’s why AHM also offers telehealth appointments.

For when you have to see your doc during your lunch break, or when the travel time is too long and too far, video visits come in clutch. Also, if you got your labs done and I have the results, then saving your travel time we can talk numbers and make decisions together without the need to be in the same room.

What the research actually shows

Researchers from FOLX Health and Brown University followed adults who initiated GAHT through a telehealth clinic and found significant reductions in depression, anxiety, and suicidal ideation after 3 months of HRT. [3] The number of people able to access and start hormone therapy would be lower if online telehealth options like FOLX Health didn’t exist. That’s worth some appreciation.

However, HRT care deserves a balanced approach, with both telehealth and in-person options helping to optimize the care given. Overall, people have high satisfaction with telehealth. [2] However, one study explicitly found that patients rated telehealth worse for starting hormone therapy, learning injection technique, and preparing for surgery. [2] Some appointment types can be telehealth, but some maybe shouldn’t be.

What the research shows

Gender-affirming HRT by the numbers

86.5%

Patient satisfaction with telehealth gender-affirming care

A majority of patients and caregivers rated telehealth visits the same or better than in-person across convenience, privacy, and provider communication.

Apple et al., Transgend Health, 2022 [2]

3 mo

Time to meaningful mental health improvement

Significant reductions in depression, anxiety, and suicidal ideation seen in adults after just 3 months of telehealth-initiated GAHT.

Corman et al., J Med Internet Res, 2025 [3]

Few

Patients who preferred telehealth for starting HRT

In a study of patients beginning hormone therapy for the first time, none rated telehealth as equal to or better than in-person for that first visit.

Apple et al., Transgend Health, 2022 [2]

=

Injection teaching: outcomes equivalent

Telehealth and in-person instruction produced equivalent testosterone levels at 3 and 6 months β€” but telehealth patients needed slightly more follow-up support afterward.

Nightingale et al., Transgend Health, 2025 [1]

28

Studies supporting gender-affirming care

A landmark systematic review found no studies identifying significant negative outcomes or harms from gender-affirming care.

Johansson et al., eClinicalMedicine, 2025 [7]

[1] Nightingale KJ et al. Transgend Health. 2025;10(4):325-333.    [2] Apple DE et al. Transgend Health. 2022;7(2):159-164.    [3] Corman JD et al. J Med Internet Res. 2025;27:e64017.    [7] Johansson T et al. eClinicalMedicine. 2025.


What Telehealth Can't Fully Replace

Starting hormones for the first time

I may be more specific in this, so not sure how generalizable it is… but I started work as a primary care physician who also offered HRT management. I was part of a large academic institution at UCLA Health, so I was funneled patients who sought out the university and then got me due to location or availability. But the longer I practiced medicine, the more I appreciated the relational aspect of care.

I like getting to know the people I’m working with so that I can better understand their goals – and then ultimately if I have a better understanding of their goals, then I can better help them achieve those goals.

I’m not talking about being friends with my patients – I’m talking about making someone comfortable enough to tell me the personal details that matter for their health. For instance, talking about erectile dysfunction as a trans woman isn’t always a comfortable discussion. And knowing the person you are discussing a sensitive matter with – knowing that person is going to respect you, maybe calm your fears – is a professional relationship worth having when going through an experience as sensitive as a puberty.

Learning injections

I’ve done both – I’ve taught injection administration both in-person and virtually. And I can tell you that in my experience, in-person is a better option for most people. In the same room, I’m able to demonstrate and then visualize patient technique better than from a single 2-dimensional perspective on a screen. Research helps back this up, showing some patients report injection teaching was better in-person vs telehealth. [2]

I would also like to mention one study that showed telehealth injection teaching was clinically equivalent to in-person. So the quality of the learning material may be similar. However, notably, the telehealth group had slightly more post-instruction follow-up contacts, suggesting patients needed more support after virtual instruction. [1]

Anything involving a physical exam

Physical exams are limited to self-reporting and what I can see with telehealth. Ya see, I can’t use my stethoscope to listen to your heart and lungs over a screen, I can’t use my BP cuff. If we want baseline vitals, or if you need a pre-op visit 30 days prior to a procedure – it will have to be done in-person.

Additionally, an in-person appointment is an opportunity to screen for other chronic health conditions such as hypertension by getting an accurate blood pressure reading. It allows the space to feel for nodules underneath the skin and assess when that needs further exploration. It means being able to show me an injection site rash or a lump or bump or change in hair or skin and I will be able to better assess what is going on because of the physical exam.


Why I Offer Both β€” and Why That Matters for Your Care

When creating AHM, I wanted to build a practice that is sustainable, practical, and accessible. This meant threading the needle between a few different concepts: affordability, accessibility, credibility… to name a few.

So for me this was not a question of virtual vs in-person gender-affirming hormone therapy management, but instead a hybrid of both. While telehealth remains an option, particularly for those quick check-ins or for logistical ease, in-person visits are not only available but sometimes recommended.

That first visit is in-person to help establish a clinical rapport and professional relationship. Injection teaching (as needed) is in-person so I can easily guide and help optimize technique on the first go. Pre-op visits are in-person to get all of the information including a physical exam for surgical preparation.

This isn’t just how I prefer to practice. The data backs it up [1,2,5,6]. With the hybrid model being ideal, that’s the direction AHM went and that’s the care I currently provide. If you want to explore more about gender-affirming hormone therapy care and process at AHM, you can visit GAHT Care & Process.  

The AHM model

Why hybrid care works

In-person when it matters. Virtual when it makes sense.

πŸ’°

Affordability

Direct care without insurance-directed medicine or 15-minute appointment slots.

βœ“ No surprise billing

βœ“ Transparent pricing

βœ“ 60-minute appointments

πŸ“

Accessibility

In-person when your care requires it or you simply want it. Virtual when it makes sense.

βœ“ Virtual follow-ups

βœ“ Lab review by video

βœ“ California-licensed telehealth

πŸŽ“

Credibility

Academic medicine background. Evidence-based practice. One physician, always.

βœ“ UCLA Health trained

βœ“ WPATH SOC8 aligned

βœ“ Same provider every visit

β™₯

The hybrid model isn't a compromise β€” it's the point

Some visits are better virtual. Some need a room. Having both means your care isn't limited by the format.


How to Choose What's Right for You

Frequently Asked Questions

Sources:

[1] Nightingale KJ, Jelinek SK, Jones C, et al. Telehealth versus in-person injection instruction for adolescents and young adults initiating gender-affirming testosterone therapy. Transgend Health. 2025;10(4):325-333. doi:10.1089/trgh.2024.0130

[2] Apple DE, Lett E, Wood S, et al. Acceptability of telehealth for gender-affirming care in transgender and gender diverse youth and their caregivers. Transgend Health. 2022;7(2):159-164. doi:10.1089/trgh.2020.0166

[3] Corman JD, Hughto JMW, Shireman TI, Baker K, Steinle K, Forcier M. Mental health changes in US transgender adults beginning hormone therapy via telehealth: longitudinal cohort study. J Med Internet Res. 2025;27:e64017. doi:10.2196/64017

[4] Coleman E, Radix AE, Bouman WP, et al. Standards of care for the health of transgender and gender diverse people, version 8. Int J Transgend Health. 2022;23(suppl 1):S1-S259. doi:10.1080/26895269.2022.2100644

[5] Dowshen N, Lett E. Telehealth for gender-affirming care: challenges and opportunities. Transgend Health. 2022;7(2):111-112. doi:10.1089/trgh.2021.0206

[6] Sequeira GM, Kahn NF, Stewart MK, et al. Outcomes research on telemedicine-delivered gender-affirming health care for transgender youth is needed now: a call to action. Transgend Health. 2023;8(1). doi:10.1089/trgh.2022.0104

[7] Johansson T, Vinther Larsen C, Zewdu S, et al. Provision of gender-affirming care for trans and gender-diverse adults: a systematic review. eClinicalMedicine (Lancet). 2025. doi:10.1016/j.eclinm.2025.103390

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How to Get HRT in Los Angeles: Dr. Fernandez's Guide